Latest Research Preprints - Life Science Network

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This list contains preprints from the last 30 days only. Use the search function to access older preprints.

The default sorting of preprints in this list is by the date when the preprint was uploaded or imported to our database (shown on top). Publication date is indicated below the title.

Created 20 Sep 2026

Identifying Putative Pathogenic Non-Coding Variants in Unresolved Rare Disease Patients Using Topologically Associated Domains

by Gacita, A. M., Pahl, M., Torres, M. D., Ganesan, S., Blair, J. J., Patel, K., Ramakrishnan, R., Conlin, L., Helbig, I., Grant, S. F. A.
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Created 09 Sep 2026

A nucleolar assembly module integrates an ancestral isoaspartylase to safeguard ribosome biogenesis
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Created 14 Sep 2026

Modular click-chemistry-based engineering minimally perturbs CRISPR ribonucleoprotein formation for genome imaging applications

by Van Tricht, C., Thonon, S., Wouters, D., Sifrim, A., Vandereyken, K., Pinheiro, V. B., Voet, T., Lammertyn, J., Spasic, D.
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Created 15 Sep 2026

Cross-platform multi-laboratory screening identifies HUWE1, USP33 and USP20 as negative-regulators of autophagy or mitophagy with relevance to neurodegeneration

by Giudici, M. L., Coode, E., Au, W. H., Rey, C., Manifava, M., Capatina, O.-G., Aldred, G., Milde, S., Zyka, V., Kuan, W.-L., Duce, J., Clarke, J. H., Whitworth, A. J., Ktistakis, N. T., Skidmore, J.
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Created 29 Sep 2026

The iron-binding siderophore enterobactin is required for the response of multi-drug resistant Klebsiella pneumoniae to zinc limitation

by Singer, J. R., Doyle, D. A., Kunkle, D. E., Burroughs, O. S., Service, R. J., Chazin, W. J., Skaar, E. P.
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Created 13 Sep 2026

Contemporary ecological heterogeneity shapes candidate adaptive genomic variation across the native range of an invasive herbivore

by Poveda-Martinez, D., PARANY, M. N. J., Salinas, N. A., Moreyra, N. N., Hasson, E., Varone, L.
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Created 12 Sep 2026

Causal variant underestimation is a major overlooked driver of sequence-to-function model underperformance

by Drusinsky, S., Pollard, K. S.
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Created 20 Sep 2026

Cross-species spatial profiling links progranulin to an immune suppressive niche in brain metastasis
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Created 15 Sep 2026

Integrated Spatial Metabolomics and Proteomics from the Same Tissue Section Using a Conductive ITO-PET Slide

by wang, h., Li, Y.
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Created 13 Sep 2026

PAR2 signaling shapes microbial and metabolic remodeling along the gut-lung axis

by Mann-Nuttel, R., Jindal, R., Armbruster, M., Mandal, S., Zhou, G., Blackman, C., Tan, M., Vliagoftis, H., Forsythe, P.
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