Preprints

Created 18 Jul 2026

Large-scale dimensional behavioral profiling dissociates fear memory from locomotor confounds in mice: The necessity of baseline-normalized metrics

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Created 10 Aug 2026

FOCUS: end-to-end preprocessing, alignment and resolution-matched integration of spatial multi-omics data

by Venturelli, L., Jacobs, J., Sifrim, A.

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Created 24 Jul 2026

Programming protein shape as an explicit design layer via CAD blueprint-guided diffusion

by Qi, Y., Zhang, G., Yserentant, K., Lee, S., Lyubimov, A., Ibrahim, K., Cimicata, G., Fraser, J. S., Huang, B., Kortemme, T.

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Created 11 Aug 2026

A Principled Statistical Framework for Analyzing Spatial Patterns in Spatially Resolved Multi-Omics

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Created 04 Aug 2026

A single-cell and multi-platform spatial atlas of the human pancreas resolves a transformation-associated epithelial axis and a recurrent boundary-organized tumour microenvironment

by Liu, K., Zhong, H., Elangovan, R. S., Sun, Y., Wang, L., Williams, A. P., Valerio, T. I., Furrer, C., Adams, J. P., Hoover, A. R., Chen, W. R.

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Created 22 Jul 2026

HDAC3 inhibitor RGFP966 acts on the NF-kB pathway and enhances memory persistence in a biphasic manner

by Robles, A. D., D'hers, S., Feld, M., Romano, A.

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Created 31 Jul 2026

Resolving Immune Lineage and Cell-State Heterogeneity in Human PBMCs via Mass Spectrometry-Based Single-Cell Proteomics

by O'Connor, S. A., Gletten, R. B., Sharma, R., Jensen, Z. N., Lovell, B., Garcia-Mansfield, K., Ghoda, L. Y., Zhang, B., Frankhouser, D. E., Rockne, R. C., Trent, J. M., Marcucci, G., Pirrotte, P.

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Created 06 Aug 2026

Spike and host glycan determinants of HKU1 airway tropism

by Creutznacher, R., Wallace, L. E., Debski-Antoniak, O. J., Drulyte, I., Hulswit, R. J. G., Beekman, J., van Kuppeveld, F. J. M., Bosch, B.-J., de Haan, C. A. M., Frank, M., Hurdiss, D. L., de Groot, R. J.

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Created 04 Aug 2026

Probing Mechanisms of Allosteric Regulation in AAA+ ATPases for Microtubule Severing and Protein Disaggregation

by Irshad, M., Walpalage, K., Zhang, Z., Gillen, M. S., Dima, R. I., Stan, G.

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Created 28 Jul 2026

A Portable Fluorescence Platform for Decentralized One-Health mcr-1 Monitoring

by Vargas-Reyes, M., Alcantara, R., Herrera, C., Townsend, M., Flores-Jimenes, K., Raymundo, C., Milon, P.

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