Preprints

Created 09 Jul 2026

Fibulin-2 transduces a matrix-to-metabolism signal in kidney fibrosis

by Gui, Y., Wang, Y., Li, W., Liu, J.-J., Dai, C., Mallari, S. M., Zheng, K., Jones, C., Shaffer, H. W., Dorsett, L. Y., Chang, T., Malowitz, B., Yu, Y., Chen, W., Liu, S., Liu, H., Liu, Y., Zhou, D.

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Created 04 Jul 2026

Inferring differentiation trajectories from T cell clonotype distributions

by Guryleva, M. V., Danielsson, M., Tibbitt, C. A., Coquet, J. M., Murrell, B.

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Created 27 Jun 2026

Small-molecule inhibition of the Orientia tsutsugamushi deubiquitylating enzyme OtDUB impairs bacterial reproduction

by Lee, M. J., Hunt, J. R., Cho, S., Chiarelli, T. J., Perry, C. N., Carlyon, J. A., Hochstrasser, M.

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Created 10 Jul 2026

The human leukemic fusion protein MLL-AF4 promotes autophagy and cell death in the fat body of Drosophila melanogaster

by Haukeland, A. L. C., Johannessen, J. A., Brathen, N. R., Bergeron, P., Formica, M., Enserink, J. M., Knaevelsrud, H.

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Created 04 Jul 2026

Distinct RNA engagements define genome import and replication elongation in alphaviruses

by Tan, Y. B., Luo, Y., Liu, P., Merits, A., Luo, D.

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Created 25 Jun 2026

Primary-Level Meta-Analysis of Diversity Outbred Mice Identifies a Fasting Plasma Trimethylamine N-Oxide (TMAO) Locus Modified by Sex and Diet

by Sutton, K., Gertz, E. R., Evans, L. W., Budke, D., Huda, N., Yam, P., Kim, M., Rutkowsky, J., Shih, D., Hartiala, J., Pomp, D., Lusis, A. J., Allayee, H., Bennett, B. J.

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Created 08 Jul 2026

Structural Mechanism of Filamentation Induced Dampening of GTP Inhibition of Glutamate Dehydrogenase

by Shan, Z., Darwish, N. I., Rivero-Gamez, A., Strutzenberg, T. C., Lyumkis, D., Horton, N. C.

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Created 08 Jul 2026

Nuclear adenosine metabolism defines a metabolic vulnerability unmasked by TP53 loss

by Urgel-Solas, J., Benito, A., Ortet, L., Kourtis, S., Abad, E., Coll Manzano, A., Shevzov-Zebrun, A., Reiter Elbaek, C., Martinez, C., Vander Heiden, M., Sdelci, S., Janic, A.

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Created 09 Jul 2026

Optimizing Signal Acquisition and Chemometric Pipelines for Micro NIR Plant Identification: Evaluating Spectral Backgrounds and Data Processing in Herbarium Specimens

by Alves, T. C., de Gasper, A. L.

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Created 20 Jun 2026

Pfcrt copy number amplification detected in a Plasmodium falciparum outbreak

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