Preprints

Created 10 Jul 2026

Trisomy 21 Impairs Development of Enteric Neural Crest-Derived Cells via SOD1-Mediated RET Dysregulation

by Singh, K., Liu, F., Zhao, A., Lohraseb, I., Davoli, T.

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Created 30 Jun 2026

High-fidelity rare structural variant detection with HiFiRE3 reduced representation via restriction enzyme ends

by Stewart, J. A., Mishler, J., Ahmed, S., Schwer, B., Glover, T. W., Wilson, T. E.

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Created 07 Jul 2026

A National Survey of 205 Canadian Biomedical Research Core Facilities Reveals Structural Challenges and Opportunities for Strengthening Canada's Research Ecosystem

by Ring, B., Hindmarch, C. C. T., Archer, S. L.

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Created 12 Jul 2026

Inbreeding depression is greater in benign than in stressful environments

by Chan, Y. F., Whitlock, R.

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Created 04 Jul 2026

Zero-Shot Metabolite Prediction from Gene Expression via Physics-Informed Graph Neural Networks

by Novella Rausell, C., Rabelink, T., Mahfouz, A.

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Created 26 Jun 2026

CNSigs: An R Package for the Identification of Copy Number Mutational Signatures

by Tallman, D., Striker, S., Byappanahalli, A. M., Stockard, S., Jenison, J., Collier, K. A., Blige, E., Vater, M., Stover, D. G.

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Created 18 Jun 2026

Development of binding and activity inhibition assays for the antibiotic resistance-associated protein PhoQ

by Addis, H., Blankenship, D., Carlson, E. E.

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Created 09 Jul 2026

Bifidobacterium pseudocatenulatum extracellular vesicles promote Ly6G+ granulocyte infiltration to inhibit melanoma tumour progression

by Nicklin, A. D., Jordan, A., Price, C. A., Rowe, M., Ilker, N., Mitchell, L., Stentz, R., Carding, S. R., Hall, L. J., Robinson, S. D.

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Created 18 Jun 2026

Servo-Actuated 3D-Printed Disposable Microvalves for Automated, Scalable Organoid Culture in Standard Incubators

by Zeraatkar, M., Ehrlich, D., Hernandez Cifuentes, J. S., Schweiger, H., Pessoa de Melo, M., Wachtel, E., Ozcakir, D., Seiler, S., Voitiuk, K., Rosen, Y., Josephson, C., Mostajo-Radji, M., Haussler, D., R. Salama, S., Teodorescu, M.

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Created 23 Jun 2026

Metabolomic Network Analysis Reveals Reorganization of Lipid and Steroid Programs Linked to Right Ventricular-Pulmonary Vascular Function in Pulmonary Hypertension

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