Preprints

Created 18 Sep 2026

Transplanted hearts assimilate the recipient's biological age

by Poganik, J. R., Matsunaga, T., Tyshkovskiy, A., Lu, A., Haghani, A., Zhou, H., Martin, F., Horvath, S., Givertz, M. M., Tullius, S. G., Gladyshev, V. N.

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Created 06 Oct 2026

Killer meiotic driver prevents chromosome loss and enhances fitness in a fungal pathogen

by Puebla-Planas, G., Doddi, A., Ayhan, D. H., Gutierrez-Escribano, P., Ma, L.-J., Lopez-Berges, M. S., Di Pietro, A.

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Created 01 Oct 2026

A genome-scale ORF screen for resilience factors that protect the RPE and restore vision in aged mice

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Created 06 Oct 2026

Psychedelics Restructure the Global Workspace of Consciousness

by Yousefi, P., Shinozuka, K., Vizeli, P., Holze, F., Becker, A. M., Muller, F., Liechti, M. E., Hasler, G., Rodriguez, C. I., Luppi, A., Mediano, P. A. M.

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Created 19 Sep 2026

Accelerated discovery of thermostable vaccines using data-efficient AI

by Tian, J., Tran, K. T. M., Pogostin, B. H., Sheridan, O., Mursalova, S., Lee, A. H., Liu, S., Hamkins, J., Antov, D., Power, A. L., Dash, Z. S., Yun, D., Konakovic Lukovic, M., Langer, R., Jaklenec, A.

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Created 03 Oct 2026

An AI-powered cloud biofoundry for autonomous biological research

by Chen, J., Volk, M., Shafaei, S., Tan, S.-I., Upadhyay, V., Singh, N., Zhong, X., Arneson, K., He, W., Wang, C., Lu, J., Sharma, A., McLaughlin, J., Berry, M., Harmon, S., Reyes, S., Heintz, G., Zhao, H.

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Created 03 Oct 2026

pH-sensitive binder design with Proton-PottsMPNN

by Jacobsen, C. P., Deweid, L., Birnbaum, F., Gormsen, L. W., Fryer, T., Jagd, U., Hald, A., Rasch, M. G., Jenkins, T., Ovchinnikov, S.

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Created 02 Oct 2026

SEEKER: A genome-scale library-on-library screening platform for deciphering T cell recognition of antigen

by Li, S., Lin, L., Wu, W., Liu, B., Ji, H., Guo, Z., Liu, Y., Wu, J., Liu, B., Zhong, L., Wang, X., Xu, H., Qi, H.

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Created 21 Sep 2026

TDP-43 dysfunction induces cryptic circular RNAs in ALS/FTD

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Created 02 Oct 2026

SIK3 links synaptic strength to sleep pressure through RhoA signaling

by Kitazono, T., Juichi, M., Nishida, K., Nomura, S., Shimizu, C., Kato, A., Iino, Y., Higashide, N., Miyanishi, K., Nakata, S., Ageta-Ishihara, N., Sawada, T., Shi, S., Funato, H., Yanagisawa, M.

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