Preprints

Created 09 Sep 2026

End-to-end plaque counting and virus titration from laboratory plate images with deep learning

by Moris, E., Costable, A., Rey, S., Ferreiro, I., Hurtado, J., Villagran, M., Luciano, L. L., Vazquez, A. E., Ramos, J., Monteiro, I., de Santiago, M. V., Moreno, P., Moratorio, G., Orlando, J. I.

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Created 15 Sep 2026

Cell type-specific histone acetylation landscape in Alzheimer's disease reveals a putative role of MITF in microglia

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Created 08 Sep 2026

Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching

by TARTICI, A., Stojkovic, M., Tian, A., Jewett, M. C., Altman, R. B., Wittmann, B. J.

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Created 16 Sep 2026

HeartVar: An LLM-Assisted Tool for Clinical Classification of Variants in Cardiovascular Disease Cohorts

by Thompson, J.-L., Das, D., Dunwoodie, S. L., Giannoulatou, E.

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Created 05 Sep 2026

NGS-RFA/FRA: A High Throughput Experimental and Computational Pipeline for Selective Mutational Scanning in Parallel

by Tureli, S., Bestebroer, T., James, S., Scheuer, R., Dahn, R., Fan, S., Turner, S., Wilks, S., Netzl, A., Hopping, A. M., Jones, T. C., Neumann, G., Kawaoka, Y., Fouchier, R. A. M., Richard, M., Smith, D. J.

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Created 03 Sep 2026

Lipid-ASO therapeutics exhibit differential tissue targeted delivery upon systemic or local CNS administration

by Roudi, S., Estupinan, H. Y., Saher, O., Barradas, C., Inganas, E., Le, H.-N., Frengen, N., Grochowski, R., Pavlova, S., Mansson Welinder, R., Nordin, J. Z., Biscans, A., Matsson, P., Zain, R., Sandberg, R., Hagemann-Jensen, M., EL Andaloussi, S.

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Created 04 Sep 2026

PhysiCelldFBA: Linking single-cell genome-scale metabolism to spatially explicit multicellular dynamics

by Hayoun Mya, O., Ruscone, M., Heiland, R., Macklin, P., Valencia, A., Ponce de Leon, M.

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Created 01 Sep 2026

Structure of an RNA polymerase ribozyme replication complex

by Strutzenberg, T. S., Horning, D. P., Cochrane, W. G., Andrade, L., Han, X., Joyce, G. F., Lyumkis, D.

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Created 10 Sep 2026

pH-Dependent Evolution of Delafloxacin and Ciprofloxacin Resistance in Pseudomonas aeruginosa from cystic fibrosis (CF) and non-CF-patients

by Ireddy, N., Bosch, A., Seth-Smith, H., Kohler, P., Babouee Flury, B.

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Created 19 Sep 2026

Neoantigen-reactive CD8+ T cell engagement marks exceptional survivors of pancreatic cancer

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