Preprints

Created 08 Aug 2026

HANSEN: An Integrated Structural and Functional Proteome Resource for Structure-Guided Drug Discovery in Mycobacterium leprae

by Vedithi, S. C., Rees, R., Malhotra, S., Munir, A., Matusevicius, M., Alsulami, A. F., Beaudoin, C. A., Sunkara, K. S., Das, M., Blundell, T. L., Floto, R. A.

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Created 19 Aug 2026

nf-sarcopipe enables integrative discovery of exercise-responsive miRNAs and miRNA/mRNA regulatory networks associated with skeletal muscle adaptation

by Poblete, N., Gomez, F., Cabas, G., Di Genova, A., Valladares, D., Moraga, C.

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Created 18 Aug 2026

Conformal Uncertainty Quantification for BayesAge Epigenetic Age Predictions

by Mboning, L., Pellegrini, M., Bouchard, L.-S.

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Created 16 Aug 2026

Activity-based chemical proteomics uncovers unexpected covalent targetsof E64d and reveals a role for cysteine cathepsins in PLD3 proteostasis.

by Hertwig, M., Kielkowski, P.

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Created 07 Aug 2026

Microbial community diversity predicts invasion resistance of freshwater biofilms against antibiotic-resistant bacteria

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Created 12 Aug 2026

Time-resolved lineage recording reveals a pre-existing, heritable cell state underlying metastatic potential

by Park, J., Chang, Y., Schiffman, J. S., Koyyalagunta, D., Somayaji, H., McQuillen, C. N., Chan, J., Morris, Q., Landau, D., Kim, H. H., Choi, J.

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Created 29 Jul 2026

Invasiveness Screening Kit (ISK) v3: an integrated multilingual decision-support platform for non-native species risk identification

by Vilizzi, L., Al-Marhoun, A.

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Created 19 Aug 2026

SILCS-Guided Feature Encoding Expands Ligand Recognition at an HBV Core Protein Interface

by Fan, Z., Jia, R., Lynch, D., Pavlova, A., McShan, A., Gumbart, J.

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Created 05 Aug 2026

Discovery of A Multi-Class Antibiotic Potentiator Against Resistant Klebsiella pneumoniae

by Harris, S., Dutta, S., Thong, W., Morris, M., Wang, Z., WANG, X.

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Created 16 Aug 2026

Autonomous Spatial Transcriptomics Analysis (ASTA): Demonstrating Performance Improvements through Clustering, Biological Annotation, and AI-Driven Discovery

by Zhang, M., Roe, M., Pollett, C., ANDREOPOULOS, W. B.

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