About
Summary
8 years of expertise in molecular biology, cell biology and biochemistry techniques. Development and validation of experimental protocols. Management and monitoring of different stage of activity research. Monitoring of experimental materials. Ability to contribute to the development of clinical research related document and materials. Good communication skills including the ability to present information to both clinical and non-clinical disciplines. Ability to present scientific data clearly and translate strategies into a work plan. Ability to mentor, train, supervise and inspire confidence in newcomers to the industry.
Ability to work autonomously, also assuming responsibility for projects and structures.Good attitude to teamwork and work experience gained during several years of university training.
Positions
Ph.D. Feb 2015 -
Education
University of Rome TRE 2012 - 2015
Degree: PhD in Biology Applied to Human Healt (Molecular and Cell Biology)
Management and monitoring of activity research of different project: 1) Study of
molecular mechanism involved in Trinucleotide repeat expansion (TNR) in a mouse
model for Huntington diseases (R6/2 mice); 2) The multiple role of hMTH1 and an
oxidized dNTPS pool in cancer and neurodegeneration (in vitro and in vivo study); 3)
Involvement of oxidized and unmodified ribonucleotides in TNR progression.
Skills
Capacity and skills acquired in Research Laboratories:
Strong experience in maintaining and expanding a colony of transgenic mice
and littermate wild-type (5 years of experience)
Genotyping Transgenic mice by PCR
Harvesting mouse organ
Isolation and maintenance of primary microglial cell cultures
Isolation and maintenance of nervous cell cultures
Maintenance of Human Carcinoma cell lines, cell separation
Molecular biology techniques: genomic DNA isolation; Polymerase chain
reaction (PCR); Expression cloning; Macromolecule blotting and probing;
Electrophoretic techniques; Construction and production of vectors for
molecular cloning
Enzymatic activity assay
Dosimetry
Calculation of enzyme kinetics with appropriate software
Band-shift assay (DNA-protein)
Immunofluorescence techniques
Immunoassays
Capacity and skills acquired in Biomedical Laboratories:
General criteria for accreditation of biomedical laboratories, preventive and
corrective actions
Informatic systems for the management of analytic data
Chemical, Hematological, Immunologic, Microscopic and Bacteriological
Diagnostic Analyzes
Ability to work autonomously, also assuming responsibility for projects and structures.
Ability to contribute to the development of clinical research related document and
materials. Development and validation of experimental protocols. Good
communication skills including the ability to present information to both clinical and non-clinical disciplines. Ability to present scientific data clearly and translate strategies
into a work plan. Ability to mentor, train, supervise and inspire confidence in
newcomers to the industry. Management and monitoring of different stage of activity
research. Monitoring of experimental materials. Knowledge of Good Clinical Practice
(GCP), Standard Operating Procedure (SOP) and Case Report Form (CRF).
Collaborations
Istituto superiore di sanità
Study of molecular mechanism involved in Trinucleotide repeat expansion (TNR) in a mouse model for Huntington diseases (R6/2 mice)
Languages
italian, english
