Authors
Creative Biogene
Summary
The microbial pharmacy has a long history. However, it was not until the beginning of World War II, when people realized the importance of antibiotics, especially penicillin, that greatly promoted the development of the microbial pharmaceutical industry. The emergence of liquid deep fermentation technology and genetic engineering technology has brought new development space for microbial pharmacy. With the increasingly serious bottleneck of traditional medicine, the microbial pharmacy will play a major role in the medical field.
Introduction
Microbes use the raw materials provided by people in their life activities to produce various metabolites through reproduction and metabolism, and the metabolites can inhibit or affect other biological functions at very low concentrations. According to the requirements of people, microbes take various means to separate and extract metabolites with medicinal effects. So far, many drugs have been produced through microbial cultivation and fermentation, including antibiotics, antioxidants, immunomodulators and genetic engineering drugs, etc.
Materials
The main research directions of intestinal microbes are the following aspects,
Explore the screening models and methods of microbial drugs.
Study the relationship between microbes and diseases, and find drug targets.
Develop microbial vaccines or drugs for the prevention and treatment of diseases.
Study the mechanism of action of microbial drugs.
Procedure
The requirements of DNA sample: total DNA ≥ 300ng, DNA concentration ≥ 10ng/μL, OD260/280 = 1.8 - 2.0.
The detection types are bacteria and fungi.
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