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Laboratory validation of enzyme-immunoassays for the non-invasive quantification of reproductive and stress hormone in amphibians

External protocol Created on 30 Apr 2014

Authors

Edward Narayan

Summary

Quantification of reproductive and stress hormones entirely non-invasively using amphibian urine samples has provided invaluable tool for understanding the biological functioning of reproductive and stress endocrine axis in rare, endangered and threatened species. This technical paper, I describe step by step methods for the laboratory validation of enzyme-immunoassays (EIAs) for the quantification of reproductive hormones (testosterone, oestradiol and progesterone) and stress hormone (corticosterone) entirely non-invasively in amphibian urine samples. These laboratory validation steps include (1) Accuracy/recovery checks, (2) Parallelism and (3) Quality control. I also present standard assay methods and together these will enable the advancement of non-invasive reproductive and stress endocrinology of amphibians.

Further details

The protocol was published on Protocol Exchange on 10 March 2014. To see the entire protocol, click on the source link.

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