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Synthesis of terpyridine-modified peptides

External protocol Created on 30 Apr 2014

Authors

Jose Mascareñas, Jesús Mosquera, Adrián Jiménez, and M Eugenio Vázquez

Summary

The synthesis of peptides with a terpyridine chelating ligand attached to a lysine side chain is described. The main advantage of this methodology relies on the introduction of the terpyridine unit while the peptide is still in the solid phase, thus avoiding reactions in solution and laborious HPLC purifications of synthetic intermediates.

Further details

The protocol was published on Protocol Exchange on 22 May 2013. To see the entire protocol, click on the source link.

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