Authors
katsutoshi Miura and Seiji Yamamoto
Summary
A scanning acoustic microscope (SAM) imaging system calculates and color codes the speed of sound (SOS). Because the harder the tissue and thus the greater the SOS, SAM can provide data on the elasticity of tissues and lesions. Areas with greater SOS correspond to those with higher concentrations of collagen or muscle fibers. Cell-poor or myxoid-degeneration areas demonstrate less SOS than the surrounding tissues. SAM offers the following benefits: (1) images are acquired in only a few minutes and do not require special staining, (2) repeated observations, even after the staining of the same section, are possible, (3) digital imaging from SOS exhibits high resolution that is comparable to that of light microscopy, (4) analysis by SAM systems is helpful for understanding echographic imaging, and (5) digitized SOS data can be statistically compared among different lesions.Further details
The protocol was published on Protocol Exchange on 15 April 2013. To see the entire protocol, click on the source link.Advertisement
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