Authors
Tim Bartels, Joanna Choi, Nora Kim, and Dennis Selkoe
Summary
Pathogenic aggregation of α-Synuclein (αSyn) is implicated in familial and sporadic Parkinson disease (PD) and several other synucleinopathies. Choosing non-denaturing conditions, we developed a several purification schemes in order to obtain αSyn from human erythrocytes, enabling researchers to employ biophysical techniques in order to elucidate its native structure and properties.Further details
The protocol was published on Protocol Exchange on 15 August 2011. To see the entire protocol, click on the source link.Advertisement
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