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Pancreatic islet transplantation to the renal subcapsule in mice

External protocol Created on 30 Apr 2014

Authors

Dong-sheng Li, Jianqiang Hao, Ya-Hong Yuan, Se Hak Yun, Jing-Bo Feng, Long-Jun Dai, and Garth L. Warnock

Summary

Mouse islet subcapsule transplantation is widely used in diabetes-related studies. Reliable and reproducible transplantation is essential to the success of those types of investigations. The present protocol presents detailed procedures on the mouse diabetic model and islet implantation. The blood glucose tracings under varied transplant circumstances are presented, covering syngeneic, allogeneic and xenogeneic islet transplantations. This protocol is straightforward and has been proven to be practical and reproducible.

Further details

The protocol was published on Protocol Exchange on 17 March 2011. To see the entire protocol, click on the source link.

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