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Enantioseparation of racemic compounds in capillary electrophoresis using cationic single isomer cyclodextrin

External protocol Created on 30 Apr 2014

Authors

Yong Wang, Yin Xiao, Siu-choon Ng, and Timothy T.Y. Tan

Summary

Capillary electrophoresis (CE) is a relatively new separation technique that provides rapid analysis with high efficiency and resolution due to the use of electric field and a variety of selective modes. Cyclodextrins are the most commonly utilized chiral selectors added into the background electrolyte to perform enantioseparation. This protocol describes an example of CE enantioseparation using a recently reported chiral selector mono-6-deoxy-6-(3R,4R-dihydroxypyrrolidine)-β-CD chloride (dhypy-CDCl).

Further details

The protocol was published on Protocol Exchange on 22 February 2011. To see the entire protocol, click on the source link.

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