Authors
Claire M Kelly
Summary
We describe the steps involved in desensitising neonatal rat pups to xenogenic tissue on or around the day of birth. This method allows animals to be desensitised to the xenogenic tissue and therefore prevents any subsequent graft rejection. Mature desensitised animals can be transplanted with similar xenogenic tissue without the need for any other form of immunosuppression, thus allowing long term experiments to be carried out.Further details
The protocol was published on Protocol Exchange on 12 March 2009. To see the entire protocol, click on the source link.Advertisement
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