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Immunostaining of spindle checkpoint proteins on Drosophila mitotic chromosomes from larval brains

External protocol Created on 03 May 2014

Authors

Mariarosaria Musar

Summary

We describe a very simple method to immunostain Drosophila mitotic chromosomes for spindle checkpoint proteins and kinetochore components. By using appropriate primary antibodies, this procedure allowed us to detect Zw10, Zwilch, Cenp-C, Cenp-meta and BubR1 on kinetochores of larval brain chromosomes. However, the same method can be used for detecting also structural components of chromosomes (our unpublished results).

Further details

The protocol was published on Protocol Exchange in 2008. To see the entire protocol, click on the source link.

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