Authors
Chilamakuri C Sekhar Reddy, Khader Shameer, Offmann Bernard, and Ramanathan Sowdhamini
Summary
Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, understanding of protein structure, function and evolution and is hence biologically relevant. Several computational methods are available to identify domains in the sequence. Domain finding algorithms often employ stringent thresholds to recognize sequence domains. Identification of additional domains can be tedious involving intense computation and manual intervention but can lead to better understanding of overall biological function. In this context, the problem of identifying new domains in the unassigned regions of a protein sequence assumes a crucial importance. We report the availability of a convenient server for the domain prediction in unassigned regions in proteins (PURE) which can be accessed at http://caps.ncbs.res.in/PURE/Further details
The protocol was published on Protocol Exchange in 2007. To see the entire protocol, click on the source link.Advertisement
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