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Lysine decarboxylase assay with cucurbituril (cucurbit-7-uril)

External protocol Created on 03 May 2014

Authors

Andreas Hennig, Hüseyin Bakirci, and Werner M. Nau

Summary

Amino acid decarboxylases, which have been previously assayed with laborious manometric, radiometric or multi-step colorimetric methods, can be assayed by the simple addition of a commercial macrocycle (cucurbit-7-uril) and a fluorescent dye (Dapoxyl) to the enzymatic mixture. The protocol refers to lysine decarboxylase, but the activity of several other amino acid decarboxylases can be similarly determined.

Further details

The protocol was published on Protocol Exchange in 2007. To see the entire protocol, click on the source link.

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