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Cell staining for sorting of hematopoietic stem cells (HSC) and myeloid progenitors and isolating RNA from sorted cells

External protocol Created on 03 May 2014

Authors

Hideyo Hirai, Pu Zhang, Tajhal Dayaram, Christopher Hetherington, Shin-ichi Mizuno, Jiro Imanishi, Koichi Akashi, and Daniel Tenen

Summary

The combination of prospective identification/isolation of bone marrow progenitors and quantitative RT-PCR is a powerful tool to understand the molecular mechanism underlying hematopoiesis. Here, we described our standard procedures of the murine myeloid progenitor staining for fluorescence activated cells sorting (FACS) and RNA purification methods.

Further details

The protocol was published on Protocol Exchange in 2006. To see the entire protocol, click on the source link.

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