Authors
Daniel Egle, Christine Brunner, Magdalena Ritter, Verena Wieser, Katharina Knoll, Birgit Amort, Afshin Soleiman, Heidelinde Fiegl, Christian Marth, Carmen Albertini, Rupert Bartsch
Published in
Breast care (Basel, Switzerland). Volume 20. Issue 2. Pages 57-65. Epub Jan 07, 2025.
Abstract
In early-stage breast cancer with initially positive axillary lymph nodes, reliable assessment of the involvement of the axilla is important because of the prognostic importance of lymph node metastases. After neoadjuvant chemotherapy (NACT), targeted axillary dissection (TAD), including sentinel lymph node biopsy and primarily involved lymph nodes, is currently regarded as the standard of care. The target lymph node must be marked using a clip/marker and later localized using a reliable guidance technique to identify the node, to avoid the indication of axillary lymph node dissection.
The present study aimed to evaluate retrospective data collected from April 25, 2022, until March 30, 2023, on a consecutive series of patients, to determine the efficacy and safety of using the Sirius Pintuition GPSDetect™ surgical marker navigation system.
This consecutive case series shows that identification of the target node with surgical marker navigation is feasible and safe, with a 100% identification rate at surgery, in a population of 20 patients with histologically verified axillary lymph node involvement before NACT.
Magnetically guided localization systems may therefore be a valid alternative to ultrasound-guided wire placement. The data highlight the practicality of the magnetically guided approach, which potentially contributes to a reduction in treatment-related morbidity by avoiding unnecessary axillary lymph node dissection.
PMID:
40256674
Bibliographic data and abstract were imported from PubMed on 21 Apr 2025.
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