The Studies on the Synthesizing Dibenzodiazocinediimine via Constructing an Eight-Membered Ring.

Authors

Bing Wang, Mengyao Mi, Shu-Jia Li, Jie-Fang Huang, Pengju Feng, Ling Lin, Yu Tang

Published in

The Journal of organic chemistry. May 09, 2025. Epub May 09, 2025.

Abstract

A one-step and facile strategy to synthesize dibenzo[b,f][1,5]diazocine-6,12(5H,11H)-diimine and its analogs via the construction of an eight-membered ring has been established using o-aminobenzonitrile or o-phenylenediamine/phthalonitrile derivatives as raw materials. Twelve compounds, including 9 new compounds, have been synthesized in yields ranging from 62-95%. Five new compounds of 5,12-dihydrodibenzo[b,f][1,4]diazocine-6,11-diimine derivatives have also been synthesized in yields of 35-52%. Furthermore, the reaction between arylnitriles and various amines was also efficiently established under similar reaction conditions. Finally, a reasonable mechanism involving sodium as a proper base to initiate the cyclization process was proposed.

PMID:
40344598
Bibliographic data and abstract were imported from PubMed on 10 May 2025.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.