Authors
Dahang Shen, Qian Bao, Feiyang Ye, Hao Li, Osama Alam, Sufen Zhang, Qingfu Ye, Jay Gan, Wei Wang
Published in
Journal of agricultural and food chemistry. May 26, 2025. Epub May 26, 2025.
Abstract
The use of neonicotinoids in agricultural seed treatments faces increased scrutiny due to their adverse effects such as induced pollinator decline. Cycloxaprid is a promising alternative to traditional neonicotinoids with higher efficiency and improved safety profiles. This study systematically investigated the uptake, translocation, and metabolism of cycloxaprid in rice, maize, and water spinach after seed treatment, using 14C isotope tracing and high-resolution mass spectrometry. Results indicated that less than 11% of cycloxaprid was absorbed by the seedlings, with over 85% released into soils. Cycloxaprid predominantly accumulated in the roots and lower leaves, with minimal translocation to upper leaves or edible parts. Subcellular analysis revealed that cycloxaprid and its metabolites predominantly bonded with internal plant matrix molecules, limiting their transport within the plants. Additionally, seven metabolites of cycloxaprid were identified, and a preliminary metabolic pathway in plants was proposed. Compared to conventional neonicotinoids, cycloxaprid displayed lower potential for plant uptake and vertical translocation, thereby reducing risks to nontarget species like pollinators. These findings provide important theoretical support for the promotion of cycloxaprid as a safe seed treatment agent and offer new perspectives for the sustainable use and risk management of neonicotinoid pesticides.
PMID:
40418663
Bibliographic data and abstract were imported from PubMed on 27 May 2025.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 15
- Comments 0