Isolation and identification of 6-methoxy parillin and coniferin from the bulbs of Allium affine L.

Authors

Narges Vakili, Mahsa Esmaeilifallah, Masoud Sadeghi Dinani

Published in

Research in pharmaceutical sciences. Volume 17. Issue 6. Pages 723-727. Epub Oct 29, 2022.

Abstract

Phytochemically, Allium species are a rich source of important secondary metabolites especially steroidal saponin and sapogenins, flavonoids, and sulfur compounds. As a member of this genus, Allium affine, which is locally known as "tareh kouhi", is an endemic plant of middle Asian countries.
Bulbs of A. affine were collected and air-dried in the shade. The chloroform-methanol (9:1) extract of the sample was subjected to purification by MPLC and HPLC. Structure elucidation of isolated compounds was done using comprehensive spectroscopic methods including 1D-NMR, 2D-NMR, and MS.
A steroidal saponin structurally related to parillin and a phenylpropanoid glycoside (coniferin) were isolated and identified from the plant chloroform-methanol extract.
To the best of our knowledge isolation of these potentially medicinal compounds from A. affine was reported for the first time in this study.

PMID:
36704434
Bibliographic data and abstract were imported from PubMed on 27 May 2025.

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