Evaluation of the transjugular intrahepatic portosystemic shunt (TIPS) surgical strategies: a computational fluid dynamics perspective.

Authors

Baopeng Wu, Hao Han, Jing Yao, Lingyu Jiang, Jian Yang, Ying Xin, Runxin Fang, Lingling Wei, Shicheng He, Zhiyong Li, Qiang Chen

Published in

Biomechanics and modeling in mechanobiology. Jun 05, 2025. Epub Jun 05, 2025.

Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) surgery is commonly employed to treat the portal hypertension (PH), and an appropriate surgical strategy is crucial to balance the surgical outcome and post-TIPS complications. This study numerically explored the effects of six TIPS surgical strategies on the shunt outcome and PV stenosis risk by considering three stent insertion positions with two in-vessel covered lengths from the perspective of the hemodynamics. Sequential CT images of 21 PH subjects were used to reconstruct the six kinds of virtual TIPS surgical models with 6 mm stent and further to compare their five post-TIPS hemodynamic indexes. According to four of the five indexes, it was found that although there was no significant difference between the six surgical strategies, the stent insertion into the main portal vein (MPV) with in-vessel covered length 0 cm was slightly better to reduce the PV pressure, improve the shunt outcome, and potentially decrease the post-TIPS PV stenosis risk. The current findings could be helpful for clinical applications in the aspect of selecting TIPS surgical strategy to treat the PH.

PMID:
40471468
Bibliographic data and abstract were imported from PubMed on 05 Jun 2025.

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