MOF-based hybrid electrodes for multi-enzyme cascade reactions with stabilized mediator immobilization.

Authors

Kotoko Ariga, Muhammad Rezki, Kayo Suzuki-Nagata, Tsutomu Mikawa, Seiya Tsujimura

Published in

Chemical communications (Cambridge, England). Jul 17, 2025. Epub Jul 17, 2025.

Abstract

ZIF67-NQS/CNT hybrid electrodes enabling stable mediator immobilization and efficient multi-enzyme cascade reactions exhibited enhanced current output attributed to the cascade effect. Notably, the pyruvate byproduct inhibited lactate oxidase activity, while its elimination via pyruvate decarboxylase significantly improved the current response. This strategy offers both mechanistic insights and practical advantages.

PMID:
40673994
Bibliographic data and abstract were imported from PubMed on 17 Jul 2025.

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