Authors
Kathrin Cresswell
Published in
BMJ health & care informatics. Volume 32. Issue 1. Jul 20, 2025. Epub Jul 20, 2025.
Abstract
Precision and genomic medicine have significant potential to improve population health. However, despite rapid technological development and increasing data complexity, practical applications of precision medicine remain limited. There is also a lack of evaluation of unintended consequences and a failure to use theory-based implementation frameworks to manage risks and ensure sustainability.
This work provides a conceptual overview of evaluation challenges related to precision medicine platforms, based on existing literature. It proposes a theory-informed proactive process evaluation framework to guide the development and assessment of these platforms.
The proposed framework considers infrastructural, socio-organisational and system-level factors. It raises key questions, such as: How will platforms integrate with existing infrastructures? How will they transform care pathways and the delivery of care across settings?
Rapid technological advances challenge markets and regulatory environments. Agile evaluation approaches are crucial for building a sustainable innovation ecosystem for precision medicine platforms.
PMID:
40685163
Bibliographic data and abstract were imported from PubMed on 21 Jul 2025.
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