Investigating the potent antimicrobial properties of a supramolecular Zn(ii)-metallogel formed from an isophthalic acid-based low molecular weight gelator.

Authors

Subhendu Dhibar, Sangita Some, Suchetana Pal, Rajlakshmi Laha, Priya Kaith, Aditi Trivedi, Subham Bhattacharjee, Lebea N Nthunya, Timothy O Ajiboye, Sumit Kumar Panja, Asit Kumar Das, Ashok Bera, Somasri Dam, Bidyut Saha

Published in

RSC advances. Volume 15. Issue 34. Pages 27544-27550. Aug 01, 2025. Epub Aug 04, 2025.

Abstract

A zinc(ii)-based metallogel was synthesized using isophthalic acid as a gelator in N,N-dimethylformamide at room temperature. The gel formation was confirmed by FT-IR spectroscopy, revealing coordination interactions responsible for network assembly. Rheological studies demonstrated the mechanical robustness and stability of the Zn(ii)-metallogel under various conditions. Field emission scanning electron microscopy (FESEM) and energy-dispersive X-ray (EDX) mapping analyses revealed a well-defined microstructure and uniform elemental distribution, providing insight into its morphology and composition. Antimicrobial evaluations showed notable inhibitory effects against both Gram-positive and Gram-negative bacterial strains, underlining the metallogel's broad-spectrum efficacy. These results indicate that the Zn(ii)-isophthalic acid metallogel holds strong promise for applications in antimicrobial materials. Its structural integrity and bioactivity suggest potential utility in biomedical and industrial domains, promoting the development of advanced multifunctional materials.

PMID:
40761907
Bibliographic data and abstract were imported from PubMed on 05 Aug 2025.

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