The Use of Dermal Substitutes for Reconstruction of Extensive Foot and Ankle Wounds.

Authors

Adi Maisel Lotan, Shirly Shohat, Gilad Spiegel, Elad Sela, Rami Binenboim, Yoav Gronovich

Published in

The Israel Medical Association journal : IMAJ. Volume 27. Issue 8. Pages 492-497.

Abstract

Soft-tissue defects of the lower limb pose a reconstructive challenge. Soft tissue loss with exposed bone, tendon, or cartilage often requires free flap reconstruction. Dermal substitutes are used for treatment of extensive burns to replace damaged skin and may be ideal for lower limb reconstruction in selected cases.
To present our experience with reconstruction of lower limb wounds using Integra® Bilayer Wound Matrix (Integra LifeSciences Corp., Plainsboro, NJ, USA) and MatriDerm® (MedSkin Solutions Dr. Suwelack AG, Billerbeck, Germany).
This single center retrospective study comprised 10 patients who underwent reconstruction of extensive tissue defects of the distal lower limbs with dermal matrices and split-thickness skin grafts.
All patients were successfully reconstructed and resumed normal ambulation. Six patients had complete and four partial graft takes that was treated conservatively until full wound healing. Older patients with medical co-morbidities or history of wound infection were more likely to have partial graft take. One postoperative infection was recorded in the study.
Dermal substitutes are easy to apply and safe, show minimal donor site morbidity, provide good functional and aesthetic outcomes, and should be used for reconstruction of complex lower limb wounds.

PMID:
40819199
Bibliographic data and abstract were imported from PubMed on 17 Aug 2025.

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