Progression of carotid plaque burden in patients with polycythemia vera and essential thrombocythemia.

Authors

Seong Soon Kwon, Sun Young Jeong, Min-Young Lee, Kyoung Ha Kim, Namsu Lee, Jong-Ho Won, Seug Yun Yoon

Published in

Blood research. Volume 60. Issue 1. Pages 48. Sep 01, 2025. Epub Sep 01, 2025.

Abstract

Prevention of vascular events is the main objective in patients with polycythemia vera (PV) or essential thrombocythemia (ET). Carotid ultrasonography (USG) is a safe and noninvasive diagnostic tool that can be used to stratify cardiovascular and stroke risks. In our previous study, carotid plaque burden was significantly higher in patients with PV/ET than in the general population. This study aimed to determine changes in carotid plaques in patients with PV/ET.
We retrospectively evaluated the medical records of patients with ET/PV who had undergone carotid USG at least twice.
Of the 56 patients, 30 had PV and 26 had ET. The carotid plaque score was increased in the follow-up carotid USG compared with that in the initial carotid USG (3.38 ± 1.47 vs. 3.73 ± 1.46, p = 0.0139). The carotid plaque burden at the time of follow-up carotid USG showed no significant differences in patients with a complete hematologic response (CHR); however, it significantly worsened in patients who failed to achieve CHR.
We confirmed that the carotid plaque burden persisted during follow-up in patients with PV/ET. A CHR may prevent an increase in carotid plaque burden.

PMID:
40888968
Bibliographic data and abstract were imported from PubMed on 02 Sep 2025.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.