Water-insensitive down-shifting nanoparticles for sensitive biosensing.

Authors

Jiang Ming, Sikun Hu, Fan Zhang

Published in

Light, science & applications. Volume 14. Issue 1. Pages 307. Sep 05, 2025. Epub Sep 05, 2025.

Abstract

Conventional optical probes suffer from signal degradation in aqueous media, hindering sensitive biodetection. To overcome this, newly developed water-insensitive down-shifting nanoparticles (WINPs) possess superior photophysical properties in the NIR-I window, including high quantum yield and negligible thermal effects, permitting stable, high-contrast signal generation under low excitation power. This advantage facilitated a low-power lateral flow assay capable of highly sensitive avian influenza virus (AIV) detection in the opaque biological matrices (such as avian swabs), mitigating interference issues relying on visible-range signals.

PMID:
40913066
Bibliographic data and abstract were imported from PubMed on 06 Sep 2025.

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