The relationship of muscle İnjury frequency with the myosin light chain Kinase (MLCK) gene and sports İnjury anxiety association of MLCK polymorphisms with sports İnjury anxiety.

Authors

Şule Özgüneş, Aylin Zekioğlu, Fethi Sırrı Çam, Mehmet Hilmi Gökmen

Published in

Research in sports medicine (Print). Pages 1-16. Sep 17, 2025. Epub Sep 17, 2025.

Abstract

The purpose of the current study is to determine the relationship between the Myosin Light Chain Kinase (MLCK) gene and muscle injuries and to reveal athletes' injury status both molecularly and psychologically using the Sports Injury Anxiety Scale. The participants of the study are 23 female and 39 male athletes who have been previously engaged in sports or are currently active in sports. The participants are aged 18-65 and participated in the study on a volunteer basis. In the current study, when the relationship between injury anxiety, genetics and injury frequency in athletes was examined, a significant correlation was found between the MLCK C49T gene region and anxiety of causing disappointment (D total) as follows: the C/C genotype 12.4 ± 2.69 p < 0.05). In the current study, the anxiety of being perceived as weak was found to be higher in the A/A genotype. A significant correlation was found between MLCK 37885a_Gene_Region and the anxiety of being perceived as weak (B_Total) as follows: A/A genotype: 6.25 ± 3.7 >C/C genotype: 4.17 ± 2.04 = 0.032(m) (p < 0.05). These results suggest that there may be a relationship between injury and some psychological and environmental factors.

PMID:
40959885
Bibliographic data and abstract were imported from PubMed on 17 Sep 2025.

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