Co-administration of histidine and soy isoflavones induces beige adipogenesis in male rats: depot-specific responses in white adipose tissue.

Authors

Riku Asahi, Haruhide Udagawa, Remiko Oshiro, Shigeru Nakajima, Nobuyuki Kanzawa, Yukiko Shimizu, Tadashi Okamura, Takahiko J Fujimi

Published in

Bioscience, biotechnology, and biochemistry. Sep 12, 2025. Epub Sep 12, 2025.

Abstract

Co-administration of histidine and soy isoflavones induced beige adipogenesis in male rats, as demonstrated by the formation of multilocular lipid droplets and increased uncoupling protein 1 gene expression in white adipose tissue. This response was accompanied by fat depot-specific enhancement of mitochondrial activity and suppression of lipogenesis, suggesting the potential for dietary strategies to combat obesity via beige adipocytes activation.

PMID:
40966667
Bibliographic data and abstract were imported from PubMed on 19 Sep 2025.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.