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Identification of a nuclear transcription factor-Y (NF-Y) gene family in pepper and analysis of a CaNF-YC1-CaTIFY7-CaCBF1a/b transcription factor module under cold stress.

Created on 02 Oct 2025

Authors

Xiaodi Wang, Kai Xu, Ning Li, Xiaohui Zhan, Shenghua Gao, Yanxu Yin, Weiling Yuan, Weifang Chen, Minghua Yao, Fei Wang

Published in

Plant physiology and biochemistry : PPB. Volume 229. Issue Pt C. Pages 110517. Sep 17, 2025. Epub Sep 17, 2025.

Abstract

Pepper is a popular crop, and its preference for a warm environment means that the frequent occurrence of extreme cold weather worldwide has increased the urgency to breed cold-tolerant vegetable varieties. The exploration of cold-tolerant genes has become a key research focus. However, research on transcription factors that regulate low-temperature tolerance in pepper plants remains limited. In this study, whole-genome analysis of the nuclear transcription factor Y (NF-Y) family was performed, revealing cold stress induction and transcription activation activity of CaNF-YC1. Silencing CaNF-YC1 increased the H2O2 content and decreased the activities of the POD, SOD, and CAT enzymes under cold stress, significantly reducing the plants' low-temperature tolerance. Conversely, overexpression of CaNF-YC1 enhanced pepper plants' tolerance to low-temperature stress. RT-qPCR, yeast one-hybrid, and analysis of GUS/LUC reporter genes in tobacco demonstrated that the CaNF-YC1 transcription factor activates expression of CaCBF1a and CaCBF1b by binding to their promoters. Yeast and tobacco assays revealed that the CaNF-YC1-CaTIFY7 complex finely regulates activation of the CaCBF1a and CaCBF1b promoters. The results indicate a crucial role for the CaNF-YC1-CaTIFY7-CaCBF1a/b molecular module in regulating core factors of low-temperature signaling in peppers.

PMID:
41032910
Bibliographic data and abstract were imported from PubMed on 02 Oct 2025.

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