Boosting Conductive Bioplastic Applications with SpyCatcher-SpyTag Technology and Cellulose Scaffolds.

Authors

Ji Hyun Lee, Eun Seo Lee, Un Jung Chae, Sung Ok Han, Jeong Eun Hyeon

Published in

Biomacromolecules. Oct 22, 2025. Epub Oct 22, 2025.

Abstract

Bioplastics offer eco-friendly alternatives to conventional plastics. This study aimed to expand the application scope of bioplastics by developing a functional material with enhanced conductivity. We recombined the SpyCatcher-SpyTag system from Streptococcus pyogenes with leghemoglobin from Glycine max to generate SpyCatcher-GmLegC₂-SpyTag, SpyCatcher-GmLegC₂-SpyCatcher, and SpyTag-GmLegC₂-SpyTag proteins, which assembled into a conductive polymer. This polymer exhibited electrical conductivity 2.5 times higher than free hemin in aqueous solution when mixed with hemin. For improved stability, SpyCatcher-GmLegC₂ was fused with a carbohydrate-binding module from Clostridium cellulovorans and integrated into bacterial cellulose scaffolds. The resulting composite showed a 141-fold increase in conductivity compared to free hemin and exhibited uniform, stable performance. This eco-friendly conductive bioplastic demonstrates strong potential for applications in wearable sensors, electronic devices, and sustainable conductive materials.

PMID:
41122779
Bibliographic data and abstract were imported from PubMed on 22 Oct 2025.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.