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Formation of metabolic water by aerobic glucose oxidation.

Created on 24 Oct 2025

Authors

Bjørn Quistorff

Published in

Fluids and barriers of the CNS. Volume 22. Issue 1. Pages 104. Oct 23, 2025. Epub Oct 23, 2025.

Abstract

A recent paper suggests that the water originating from the ATP production coupled to aerobic glucose oxidation causes more than a 6 fold increase in the production of metabolic water, compared with the standard textbook description of the oxidation process. However, the authors seem to have forgotten that the simultaneous processes of ATP utilization takes up the same amount of water, which was liberated during the ATP synthesis. Thus, at steady state, there is no net increase in the production of metabolic water.

PMID:
41131570
Bibliographic data and abstract were imported from PubMed on 24 Oct 2025.

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