Pro and con for systematic screening for prostate cancer in Denmark - a review article.

Authors

Signe Benzon Larsen, Andreas Røder

Published in

Danish medical journal. Volume 72. Issue 11. Oct 16, 2025. Epub Oct 16, 2025.

Abstract

Systematic PSA-based screening for prostate cancer remains controversial due to the trade-off between reduced mortality and risk of overdiagnosis and overtreatment. Adding new tools like magnetic-resonance-imaging-targeted biopsies and genetic markers may limit the harms, but we lack definitive mortality data. While opportunistic PSA testing is widely used in Denmark, unsystematic use may potentially be harmful. Introduction of a systematic screening programme in Denmark requires careful consideration of the clinical, psychological, societal and economic impacts, and Danish politicians should thus engage in the debate to clarify these issues.

PMID:
41133336
Bibliographic data and abstract were imported from PubMed on 24 Oct 2025.

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