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International Society of Sports Nutrition Position Stand: Long-Chain Omega-3 Polyunsaturated Fatty Acids.

Created on 09 Dec 2025

Authors

Ralf Jäger, Jeffery L Heileson, Sidney Abou Sawan, Broderick L Dickerson, Megan Leonard, Richard B Kreider, Chad M Kerksick, Stephen M Cornish, Darren G Candow, Dean M Cordingley, Scott C Forbes, Grant M Tinsley, Tindaro Bongiovanni, Roberto Cannataro, Bill I Campbell, Shawn M Arent, Jeffrey R Stout, Douglas S Kalman, Jose Antonio

Published in

Journal of the International Society of Sports Nutrition. Volume 22. Issue 1. Pages 2441775. Epub Jan 15, 2025.

Abstract

Position Statement: The International Society of Sports Nutrition (ISSN) presents this position based on a critical examination of the literature surrounding the effects of long-chain omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation on exercise performance, recovery, and brain health. This position stand is intended to provide a scientific foundation for athletes, dietitians, trainers, and other practitioners regarding the effects of supplemental ω-3 PUFA in healthy and athletic populations. The following conclusions represent the official position of the ISSN: Athletes may be at a higher risk for ω-3 PUFA insufficiency.Diets rich in ω-3 PUFA, including supplements, are effective strategies for increasing ω-3 PUFA levels.ω-3 PUFA supplementation, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), has been shown to enhance endurance capacity and cardiovascular function during aerobic-type exercise.ω-3 PUFA supplementation may not confer a muscle hypertrophic benefit in young adults.ω-3 PUFA supplementation in combination with resistance training may improve strength in a dose- and duration-dependent manner.ω-3 PUFA supplementation may decrease subjective measures of muscle soreness following intense exercise.ω-3 PUFA supplementation can positively affect various immune cell responses in athletic populations.Prophylactic ω-3 PUFA supplementation may offer neuroprotective benefits in athletes exposed to repeated head impacts.ω-3 PUFA supplementation is associated with improved sleep quality.ω-3 PUFA are classified as prebiotics; however, studies on the gut microbiome and gut health in athletes are currently lacking.

PMID:
39810703
Bibliographic data and abstract were imported from PubMed on 09 Dec 2025.

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