SEMPLR: an R package for transcription factor binding prediction.

Authors

Grace E Kenney, Rintsen N Sherpa, Jeremy D Burgess, Alan P Boyle, Douglas H Phanstiel

Published in

Bioinformatics (Oxford, England). Jun 12, 2026. Epub Jun 12, 2026.

Abstract

SEMPLR is an R package that predicts transcription factor binding and variant effects using SNP Effect Matrices (SEMs), providing efficient, genome-wide scoring, enrichment testing, and visualization tools for comprehensive analysis of regulatory sequences.
Available on GitHub at https://github.com/grkenney/SEMPLR and on Bioconductor at https://bioconductor.org/packages/release/bioc/html/SEMPLR.html.
Supplementary data are available at Bioinformatics online.

PMID:
42286344
Bibliographic data and abstract were imported from PubMed on 13 Jun 2026.

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