Clinical efficacy analysis of percutaneous balloon compression in patients with trigeminal neuralgia.

Authors

Yihui Du, Yinzhan Wang, Wenchang Guo, Zenghui Xi, Guozhu Sun, Tao Qian

Published in

Journal of neurosurgery. Pages 1-11. Jun 19, 2026. Epub Jun 19, 2026.

Abstract

This study aimed to assess the clinical effectiveness of percutaneous balloon compression (PBC) for trigeminal neuralgia (TN) and develop a predictive model for treatment outcomes.
A retrospective analysis was conducted of TN patients who underwent PBC between September 2020 and September 2023. Propensity score matching was used to match ineffective and effective cases at a 1:4 ratio. Perioperative data were analyzed using t-tests and chi-square tests. LASSO (least absolute shrinkage and selection operator) regression identified relevant predictors, which were then used to build a multivariate logistic regression model.
Among 230 matched patients, PBC was ineffective in 46 and effective in 184. Perioperative parameters differed significantly between the groups, while demographics did not. Balloon volume, compression duration, balloon pressure, and shape were identified as predictors of treatment outcomes. The model achieved an area under the curve of 0.890, indicating strong discriminative ability.
PBC showed significant efficacy in treating TN. Balloon volume, compression duration, pressure, and shape were independent predictors of treatment outcomes.

PMID:
42320057
Bibliographic data and abstract were imported from PubMed on 20 Jun 2026.

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