Previously unreported translocation (14;15)(q32; q11.2) observed in B-cell acute lymphoblastic leukemia: a case report.

Authors

Maliha Naz, Jawad Hassan, Neelum Mansoor

Published in

Molecular cytogenetics. Jun 19, 2026. Epub Jun 19, 2026.

Abstract

t(14;15) have rarely been seen in hematologic malignancies. Here we have reported a case of a 4-year-old male who presented with low grade fever and body aches and, was diagnosed on immunophenotyping as B-cell Acute Lymphoblastic Leukemia. Cytogenetic analysis demonstrated a previously unreported translocation t(14;15)(q32;q11.2). Fluorescent in situ hybridization (FISH) analysis on metaphases was also carried out to confirm the chromosomal aberration. To our knowledge, such a translocation has not been reported in hematological malignancy specifically in B-cell ALL.

PMID:
42321849
Bibliographic data and abstract were imported from PubMed on 20 Jun 2026.

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