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Group, Subgroup and Person-Specific Longitudinal Associations Between Physical Activity and Affect in Individuals With and Without Depressive and Anxiety Disorders.

Created on 20 Jun 2026

Authors

Noa van Zwieten, George Aalbers, Femke Lamers, Harriëtte Riese, Manon H J Hillegers, Brenda W J H Penninx

Published in

International journal of methods in psychiatric research. Volume 35. Issue 2. Pages e70085.

Abstract

Associations between physical activity and affect (activity-affect dynamics) vary among individuals for which reasons remain unclear. We examined whether such heterogeneity is explained by psychiatric status or sociodemographic, clinical, and ambulatory assessment characteristics.
Two-week ambulatory assessment data of 300 participants with current (n = 79), subthreshold (n = 67), and no (n = 154) depressive and/or anxiety disorders or symptoms were obtained from the Netherlands Study of Depression and Anxiety. Positive and negative affect (PA/NA) were assessed with ecological momentary assessment (5xdaily) and physical activity using actigraphy. Group iterative multiple model estimation was used to model associations shared across the sample, psychiatric subgroups, and those specific to individuals.
No activity-affect associations were shared across the sample (i.e., present in > 75% of all individuals) or psychiatric subgroups (i.e., present in > 51% of individuals within subgroups). Nevertheless, 45% of participants had at least one activity-affect association, with considerable heterogeneity in their nature. The most frequent association was a positive contemporaneous association between physical activity and PA (present in 25% of the sample).
These findings suggest large heterogeneity in activity-affect dynamics among individuals and underscore the importance of considering the unique dynamics of the individual.

PMID:
42322033
Bibliographic data and abstract were imported from PubMed on 20 Jun 2026.

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