Authors
Søren Søndergaard, S Madsen
Published in
Physiological reports. Volume 14. Issue 12. Pages e70987.
Abstract
Hereditary Hemorrhagic Telangiectasia (HHT) may present with symptoms arising from multiple organ systems. In this case report, the focus is on cardiovascular manifestations, including total blood volume, cardiac function, and the potential role of the sympathetic nervous system (SNS) in the clinical picture. The commonly held supposition that the cardiac hyperdynamic state in HHT is associated with increased SNS activity is examined by combining spectral analysis of heart rate variability with carbon monoxide-based measurement of total blood volume and transthoracic echocardiography. The observations are consistent with Guytonian venous return physiology and suggest a circulation characterized by low venous return resistance.
PMID:
42324622
Bibliographic data and abstract were imported from PubMed on 22 Jun 2026.
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