Exercise-induced esterified cholesterol transfer to HDL is enhanced in master endurance-trained athletes after moderate-intensity cycling.

Authors

Fábio S Lira, Caique Figueiredo, Barbara Antunes, Matheus Uba Chupel, Ricardo Ribeiro Agostinete, Herbert Gustavo Simões, Alberto Jimenez Maldonado, Dayene Bárbara, Fatima Freitas, Raul C Maranhão, Luciele Guerra Minuzzi

Published in

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. Jun 22, 2026. Epub Jun 22, 2026.

Abstract

This cross-sectional study compared basal and exercise-induced cholesterol transfer to HDL and related metabolic markers in young (n = 7) and master (n = 12) endurance-trained athletes performing a standardized 30-min moderate-intensity cycling bout. Despite similar lipid profiles, exercise intensity, and metabolic load in both groups, only master athletes showed a significant post-exercise increase in esterified cholesterol transfer to HDL (p = 0.012), whereas HDL-C remained unchanged. These findings suggest that lifelong endurance training may preserve specific aspects of HDL functionality across ageing, even in the absence of differences in conventional lipid measures, with potential relevance for cardiovascular protection.

PMID:
42330546
Bibliographic data and abstract were imported from PubMed on 23 Jun 2026.

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