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Small-number effects limit chromosome segregation synchrony.

Created on 23 Jun 2026

Authors

Andreas Boland

Published in

The Journal of cell biology. Volume 225. Issue 7. Jul 06, 2026. Epub Jun 23, 2026.

Abstract

Feedback loops have been described as universal, recurring motifs that regulate major cell cycle transitions. In this issue, Williams et al. (https://doi.org/10.1083/jcb.202602088) show, however, that chromosome segregation synchrony in fission yeast is feedback-independent, and instead, temporal precision of anaphase is dictated by molecular noise arising from small-number stochastic effects.

PMID:
42334387
Bibliographic data and abstract were imported from PubMed on 23 Jun 2026.

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