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Experimental measurement of kQ values for 150 MeV proton beams in the middle of SOBP using water calorimetry and comparison with TRS-398 rev.1.

Created on 24 Jun 2026

Authors

In Jung Kim, Jong In Park, Chul-Young Yi, Yunho Kim, Young-Min Seong, Seongmoon Jung, Inhak Yoon, Rukundo Solomon, Jong Hwi Jeong, Seonghoon Jeong, Chae-Eon Kim, Sang-Il Park, Sangmin Lee, Se Byeong Lee

Published in

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB). Volume 148. Pages 105838. Jun 23, 2026. Epub Jun 23, 2026.

Abstract

This study aimed to experimentally determine beam quality correction factors (kQ) for NE2571 and PTW 30013 chambers in clinical proton beams using water calorimetry and to compare the results with the TRS-398 rev.1 (2024).
Measurements were performed in the middle of the spread-out Bragg peak of a 150 MeV double-scattered proton beam (Rres = 7.5 g cm-2). kQ values were derived by comparing chamber readings with the absorbed dose to water determined by a sealed-water calorimeter operating at 4 ∘C.
The determined kQ values were 1.015 ± 0.009 (NE2571) and 1.012 ± 0.009 (PTW 30013). The NE2571 chamber showed excellent agreement with TRS-398 rev.1 (2024), with a deviation of only 0.7 %. The PTW 30013 exhibited a larger deviation (1.3 %), although within the standard uncertainty of the protocol. Derived (pch/ pdis)Q values were consistent with scattered beam literature but showed systematic differences compared to for scanned beams.
Results validate TRS-398 rev.1 (2024) for the NE2571 under scattered beam conditions. However, the PTW 30013 deviation and observed trends in (pch/ pdis)Q warrant further investigation into chamber-specific responses and the influence of beam delivery modalities.

PMID:
42335516
Bibliographic data and abstract were imported from PubMed on 24 Jun 2026.

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