Authors
Emily McGibbon, Elizabeth Iuppa Burke, Elizabeth Watts, Bri Beaver-Timmons, Vincent Law, Yin Ling Leung, Anupa George, Lia Qiu, Stefan Silver, Vasudha Reddy, Enoma Omoregie, Ulrike Siemetzki-Kapoor, Diane Fung, Corinne Schiff, Shama Desai Ahuja
Published in
NEJM evidence. Volume 5. Issue 7. Pages EVIDpha2600062. Epub Jun 23, 2026.
Abstract
AbstractCooling tower systems have been the source of multiple large Legionnaires' disease outbreaks. We report a July-August 2025 outbreak in the Central Harlem area of New York City, with 118 confirmed cases and seven deaths. An investigation was initiated on the day the daily spatiotemporal cluster detection analysis by the New York City Health Department noted eight positive urine antigen test results for Legionella pneumophila serogroup 1. A total of 43 cooling tower systems were sampled by day 3. Whole-genome sequencing analysis suggested that the available clinical isolates were highly related to those from two cooling towers located on the same city block.
PMID:
42334300
Bibliographic data and abstract were imported from PubMed on 24 Jun 2026.
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