Surgical treatment of acute empyema caused by methicillin-resistant Staphylococcus aureus in a patient with advanced non-small cell lung cancer: a case report.

Authors

Nozomu Motono, Mashahito Ishikawa, Shun Iwai, Yoshihito Iijima, Hidetaka Uramoto

Published in

Journal of surgical case reports. Volume 2026. Issue 6. Pages rjaf1027. Epub Jun 22, 2026.

Abstract

A 75-year-old man presented to our hospital with fever and bloody sputum. Chest computed tomography revealed a mass lesion occupying the left lower lobe with surrounding infiltrative shadows. ¹⁸F-fluoro-2-deoxy-glucose positron emission tomography demonstrated high ¹⁸F-fluoro-2-deoxy-glucose uptake in the pulmonary mass, left hilar lymph nodes, and right mediastinal lymph node. Transbronchial biopsy confirmed squamous cell carcinoma. The patient was diagnosed with clinical stage IIIC non-small cell lung cancer, and chemoradiotherapy was planned. However, 21 days after the biopsy, he developed acute empyema. Decortication was successfully performed by video-assisted thoracic surgery. Postoperatively, the antimicrobial agent was switched from meropenem hydrate to linezolid after methicillin-resistant Staphylococcus aureus was detected in the pleural effusion culture. The chest tubes were removed 7 days after surgery, and the patient was discharged 1 month after surgery. Chest computed tomography at 1.5 months postoperatively showed no recurrence of empyema, and chemotherapy for advanced non-small cell lung cancer was initiated.

PMID:
42338713
Bibliographic data and abstract were imported from PubMed on 24 Jun 2026.

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