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Non-Contact Mechanics of Soft and Liquid Interfaces by Hydrodynamic Confinement Using a Frequency-Modulated AFM.

Created on 24 Jun 2026

Authors

Lucie Corral, Christian Curtil, Medhi Lagaize, Marc Leonetti, Hubert R Klein

Published in

Langmuir : the ACS journal of surfaces and colloids. Jun 24, 2026. Epub Jun 24, 2026.

Abstract

Measuring the mechanical response of liquid interfaces without direct contact remains a major experimental challenge, particularly in liquid-liquid systems where no solid reference exists. Here, we develop a frequency-modulation atomic force microscopy (FM-AFM) method to probe liquid interfaces through the hydrodynamic confinement of a viscous liquid film between an oscillating probe and the interface. This approach provides simultaneous access to the in-phase and dissipative components of the effective mechanical response under confinement. Initially, the method is validated on a liquid-solid interface, where the measured confinement thickness and the evolution of the mechanical impedance are consistent with elastohydrodynamic theory over nearly one decade in elastic modulus. It is then applied to a liquid-liquid interface, which exhibits a predominantly viscous response with a finite in-phase contribution and a confinement thickness in the micrometric range. These results show that hydrodynamic confinement provides a sensitive, noncontact approach to compare the mechanical responses of soft and liquid interfaces, and opens perspectives for investigating complex and highly deformable systems such as polymer films, biological membranes, and rafts of nanoparticles.

PMID:
42339599
Bibliographic data and abstract were imported from PubMed on 24 Jun 2026.

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