Bordetella pertussis: emerging epidemiology, diagnosis and management.

Authors

Samuel W L Baumgart, Isaac Freelander, Winkie Fong, Sharon C-A Chen, Vitali Sintchenko, Kerri Basile, Deborah Marriott, Jen Kok

Published in

Pathology. May 28, 2026. Epub May 28, 2026.

Abstract

Bordetella pertussis is the causative agent of whooping cough, a major vaccine-preventable infection that has seen epidemic case numbers in recent years in Australia and worldwide. This manuscript reviews the performance of Bordetella diagnostic tests with a renewed focus on bacterial culture, phenotypic and genotypic susceptibility testing and molecular typing methods, against the backdrop of an observed increase in case numbers, emerging macrolide resistance and the development of pertactin-deficient strains. It highlights the need for improved diagnostics to detect and characterise macrolide resistance.

PMID:
42342467
Bibliographic data and abstract were imported from PubMed on 25 Jun 2026.

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